Vitamin D insufficiency is very common in the UK and deficiency can have adverse health effects at any stage of life. It is best known for its role in calcium and bone metabolism, but emerging research indicates that low levels of vitamin D may be associated with increased risk of some cancers, type 2 diabetes mellitus, multiple sclerosis, cardiovascular disease, rheumatoid arthritis, depression, Alzheimer’s disease, infections, preeclampsia, and neurocognitive dysfunction. Vitamin D regulates the expression of a vast array of genes in tissues, including immune cells, the vasculature, muscle and reproductive organs.
25-hydroxyvitamin D is the major circulating form of vitamin D and occurs in 2 forms: vitamin D2 (ergocalciferol) and vitamin D3 (cholecalciferol), and is the precursor of the active form (1,25-dihydroxyvitamin D). Measurement of total 25-hydroxy-vitamin D (D2 plus D3) provides the best assessment of patient vitamin D status and includes vitamin D derived from diet, supplements and exposure to UVB sunlight.
NOTE: This test is a bloodspot, so can be conducted at home and then the sample posted to the laboratory, i.e. no blood draw is required, just a finger prick.
Here’s a sample report so you can see what you’d be getting.